Constitutive Spinal Cyclooxygenase-2 Participates in the Initiation of Tissue Injury-Induced Hyperalgesia

Inhibitors of the isozyme cyclooxygenase-2 (COX-2) represent an important advance in pain management, although where and when these inhibitors can exert their antihyperalgesic actions are not completely understood. Here we show that unlike many peripheral tissues in which COX-2 is only expressed in...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ghilardi, Joseph R., Svensson, Camilla I., Rogers, Scott D., Yaksh, Tony L., Mantyh, Patrick W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729511/
https://ncbi.nlm.nih.gov/pubmed/15028765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5054-03.2004
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