p35/Cyclin-Dependent Kinase 5 Phosphorylation of Ras Guanine Nucleotide Releasing Factor 2 (RasGRF2) Mediates Rac-Dependent Extracellular Signal-Regulated Kinase 1/2 Activity, Altering RasGRF2 and Microtubule-Associated Protein 1b Distribution in Neurons

Cyclin-dependent kinase 5 (Cdk5) is a proline-directed kinase the activity of which is dependent on association with its neuron-specific activators, p35 and p39. Cdk5 activity is critical for the proper formation of cortical structures and lamination during development. In the adult nervous system,...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kesavapany, Sashi, Amin, Niranjana, Zheng, Ya-Li, Nijhara, Ruchika, Jaffe, Howard, Sihag, Ram, Gutkind, J. Silvio, Takahashi, Satoru, Kulkarni, Ashok, Grant, Philip, Pant, Harish C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729444/
https://ncbi.nlm.nih.gov/pubmed/15128856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0690-04.2004
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