Passive or Active Immunization with Myelin Basic Protein Impairs Neurological Function and Exacerbates Neuropathology after Spinal Cord Injury in Rats

Myelin-reactive T-cells are activated by traumatic spinal cord injury (SCI) in rodents and humans. Despite the historical association of these cells with experimental and clinical neuropathology, recent data suggest a neuroprotective role for myelin-reactive T-cells. Because of the biological and th...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Jones, T. Bucky, Ankeny, Daniel P., Guan, Zhen, McGaughy, Violeta, Fisher, Lesley C., Basso, D. Michele, Popovich, Phillip G.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2004
Subjects:
Neurobiology of Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729355/
https://ncbi.nlm.nih.gov/pubmed/15084655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0406-04.2004
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