B cells produce pathogenic antibodies and impair recovery after spinal cord injury in mice

Traumatic injury to the mammalian spinal cord activates B cells, which culminates in the synthesis of autoantibodies. The functional significance of this immune response is unclear. Here, we show that locomotor recovery was improved and lesion pathology was reduced after spinal cord injury (SCI) in...

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Detaylı Bibliyografya
Asıl Yazarlar: Ankeny, Daniel P., Guan, Zhen, Popovich, Phillip G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752085/
https://ncbi.nlm.nih.gov/pubmed/19770513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39780
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