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B cells produce pathogenic antibodies and impair recovery after spinal cord injury in mice

Traumatic injury to the mammalian spinal cord activates B cells, which culminates in the synthesis of autoantibodies. The functional significance of this immune response is unclear. Here, we show that locomotor recovery was improved and lesion pathology was reduced after spinal cord injury (SCI) in...

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Bibliographic Details
Main Authors: Ankeny, Daniel P., Guan, Zhen, Popovich, Phillip G.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752085/
https://ncbi.nlm.nih.gov/pubmed/19770513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39780
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