Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats

Spinal cord injury (SCI) impairs sensory systems causing chronic allodynia. Mechanisms underlying neuropathic pain have been more extensively studied following peripheral nerve injury than after central trauma. Microglial activation, pro-inflammatory cytokine production and activation of p38 MAP kin...

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Autors principals: Detloff, Megan Ryan, Fisher, Lesley C., McGaughy, Violetta, Longbrake, Erin E., Popovich, Phillip G., Basso, D.Michele
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600773/
https://ncbi.nlm.nih.gov/pubmed/18511041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.04.009
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