Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats

Spinal cord injury (SCI) impairs sensory systems causing chronic allodynia. Mechanisms underlying neuropathic pain have been more extensively studied following peripheral nerve injury than after central trauma. Microglial activation, pro-inflammatory cytokine production and activation of p38 MAP kin...

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Main Authors: Detloff, Megan Ryan, Fisher, Lesley C., McGaughy, Violetta, Longbrake, Erin E., Popovich, Phillip G., Basso, D.Michele
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600773/
https://ncbi.nlm.nih.gov/pubmed/18511041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.04.009
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