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Polymorphisms in miRNAs Gene (146a, 149, 196a) and Susceptibility to ARV-associated Hepatotoxicity

BACKGROUND: Micro RNAs act as a regulatory layer for pharmacogenomics-related gene ex-pression. It could play a role in the efficacy and toxicity of the drug. The SNPs in miRNA genes are linked with different functional consequences. METHODS: Hence, we examined the miR (146a G/C, 149C/T, and 196aC/T...

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發表在:Curr Genomics
Main Authors: Singh, Hari Om, Jadhav, Sushma, Samani, Dharmesh, Dhole, Tapan N.
格式: Artigo
語言:Inglês
出版: Bentham Science Publishers 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728905/
https://ncbi.nlm.nih.gov/pubmed/31555064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1389202920666190325161439
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