Occurrence of CYP2B6 516G>T polymorphism in patients with ARV‐associated hepatotoxicity

BACKGROUND: Hepatic enzyme cytochrome P450 2B6 (CYP2B6) plays a role in the metabolism of efavirenz drugs. CYP2B6 516G>T variation showed an implication for HIV treatment. METHODS: CYP2B6 516G>T polymorphism was genotyped in a total 165 HIV patients that include 34 with and 131 without hepatot...

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Bibliographic Details
Published in:Mol Genet Genomic Med
Main Authors: Singh, HariOm, Lata, Sonam, Dhole, T. N., Gangakhedkar, Raman R.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465650/
https://ncbi.nlm.nih.gov/pubmed/30864294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.598
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