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IL-1RN and IL-1β Polymorphism and ARV-Associated Hepatotoxicity

The severity of hepatic injury depends upon cytokines. Previous studies associated IL-1RN allele 2 with IL-1β production. Hence, we examined the association of IL-1 RN and IL-1β polymorphisms with ARV-associated hepatotoxicity. Genotyping of IL-1RN (VNTR), IL-1β (-511C/T) polymorphisms was done in 1...

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Bibliographic Details
Published in:Mediators Inflamm
Main Authors: Singh, HariOm, Samani, Dharmesh, Nema, Vijay, Ghate, Manisha V., Gangakhedkar, R. R.
Format: Artigo
Language:Inglês
Published: Hindawi 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911319/
https://ncbi.nlm.nih.gov/pubmed/29849489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4398150
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