Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice

Neurological complications affecting the central nervous system have been reported in adult patients infected by Zika virus (ZIKV) but the underlying mechanisms remain unknown. Here, we report that ZIKV replicates in human and mouse adult brain tissue, targeting mature neurons. ZIKV preferentially t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Figueiredo, Claudia P., Barros-Aragão, Fernanda G. Q., Neris, Rômulo L. S., Frost, Paula S., Soares, Carolina, Souza, Isis N. O., Zeidler, Julianna D., Zamberlan, Daniele C., de Sousa, Virginia L., Souza, Amanda S., Guimarães, André Luis A., Bellio, Maria, Marcondes de Souza, Jorge, Alves-Leon, Soniza V., Neves, Gilda A., Paula-Neto, Heitor A., Castro, Newton G., De Felice, Fernanda G., Assunção-Miranda, Iranaia, Clarke, Julia R., Da Poian, Andrea T., Ferreira, Sergio T.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728367/
https://ncbi.nlm.nih.gov/pubmed/31488835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11866-7
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker