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Cell-free mixing of Escherichia coli crude extracts to prototype and rationally engineer high-titer mevalonate synthesis

Cell-free metabolic engineering (CFME) is advancing a powerful paradigm for accelerating the design and synthesis of biosynthetic pathways. However, as most cell-free biomolecule synthesis systems to date use purified enzymes, energy and cofactor supply can be limiting. To address this challenge, we...

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Detalhes bibliográficos
Publicado no:ACS Synth Biol
Main Authors: Dudley, Quentin M., Anderson, Kim C., Jewett, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728267/
https://ncbi.nlm.nih.gov/pubmed/27476989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.6b00154
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