Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts

Cancer-associated fibroblasts (CAFs) are major players in the progression and drug resistance of pancreatic ductal adenocarcinoma (PDAC). CAFs constitute a diverse cell population consisting of several recently described subtypes, although the extent of CAF heterogeneity has remained undefined. Here...

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Veröffentlicht in:Cancer Discov
Hauptverfasser: Elyada, Ela, Bolisetty, Mohan, Laise, Pasquale, Flynn, William F., Courtois, Elise T., Burkhart, Richard A., Teinor, Jonathan A., Belleau, Pascal, Biffi, Giulia, Lucito, Matthew S., Sivajothi, Santhosh, Armstrong, Todd D., Engle, Dannielle D., Yu, Kenneth H., Hao, Yuan, Wolfgang, Christopher L., Park, Youngkyu, Preall, Jonathan, Jaffee, Elizabeth M., Califano, Andrea, Robson, Paul, Tuveson, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727976/
https://ncbi.nlm.nih.gov/pubmed/31197017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-0094
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