Phenotypic and Genotypic Consequences of CRISPR/Cas9 Editing of the Replication Origins in the rDNA of Saccharomyces cerevisiae

The complex structure and repetitive nature of eukaryotic ribosomal DNA (rDNA) is a challenge for genome assembly, thus the consequences of sequence variation in rDNA remain unexplored. However, renewed interest in the role that rDNA variation may play in diverse cellular functions, aside from ribos...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Sanchez, Joseph C., Ollodart, Anja, Large, Christopher R. L., Clough, Courtnee, Alvino, Gina M., Tsuchiya, Mitsuhiro, Crane, Matthew, Kwan, Elizabeth X., Kaeberlein, Matt, Dunham, Maitreya J., Raghuraman, M. K., Brewer, Bonita J.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2019
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727806/
https://ncbi.nlm.nih.gov/pubmed/31292210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302351
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