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Mechanical stability of αT-catenin and its activation by force for vinculin binding

αT (Testes)-catenin, a critical factor regulating cell–cell adhesion in the heart, directly couples the cadherin-catenin complex to the actin cytoskeleton at the intercalated disk (ICD), a unique cell–cell junction that couples cardiomyocytes. Loss of αT-catenin in mice reduces plakophilin2 and conn...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Pang, Si Ming, Le, Shimin, Kwiatkowski, Adam V., Yan, Jie
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727763/
https://ncbi.nlm.nih.gov/pubmed/31318313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-02-0102
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