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Functional analysis and importance for host cell infection of the Ca(2+)-conducting subunits of the mitochondrial calcium uniporter of Trypanosoma cruzi

We report here that Trypanosoma cruzi, the etiologic agent of Chagas disease, possesses two unique paralogues of the mitochondrial calcium uniporter complex TcMCU subunit that we named TcMCUc and TcMCUd. The predicted structure of the proteins indicates that, as predicted for the TcMCU and TcMCUb pa...

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Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Chiurillo, Miguel A., Lander, Noelia, Bertolini, Mayara S., Vercesi, Anibal E., Docampo, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727756/
https://ncbi.nlm.nih.gov/pubmed/31091170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-03-0152
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