Xenografting of human umbilical mesenchymal stem cells from Wharton’s jelly ameliorates mouse spinocerebellar ataxia type 1

BACKGROUND: Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disorder caused by the expansion of CAG repeats in ATXN1 gene resulting in an expansion of polyglutamine repeats in the ATXN1 protein. Unfortunately, there has yet been any effective treatment so far for SCA1...

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Gepubliceerd in:Transl Neurodegener
Hoofdauteurs: Tsai, Pei-Jiun, Yeh, Chang-Ching, Huang, Wan-Jhen, Min, Ming-Yuan, Huang, Tzu-Hao, Ko, Tsui-Ling, Huang, Pei-Yu, Chen, Tien-Hua, Hsu, Sanford P. C., Soong, Bing-Wen, Fu, Yu-Show
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727337/
https://ncbi.nlm.nih.gov/pubmed/31508229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-019-0166-8
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