Xenografting of human umbilical mesenchymal stem cells from Wharton’s jelly ameliorates mouse spinocerebellar ataxia type 1

BACKGROUND: Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disorder caused by the expansion of CAG repeats in ATXN1 gene resulting in an expansion of polyglutamine repeats in the ATXN1 protein. Unfortunately, there has yet been any effective treatment so far for SCA1...

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Publicado en:Transl Neurodegener
Autores principales: Tsai, Pei-Jiun, Yeh, Chang-Ching, Huang, Wan-Jhen, Min, Ming-Yuan, Huang, Tzu-Hao, Ko, Tsui-Ling, Huang, Pei-Yu, Chen, Tien-Hua, Hsu, Sanford P. C., Soong, Bing-Wen, Fu, Yu-Show
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727337/
https://ncbi.nlm.nih.gov/pubmed/31508229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-019-0166-8
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