Xenografting of human umbilical mesenchymal stem cells from Wharton’s jelly ameliorates mouse spinocerebellar ataxia type 1

BACKGROUND: Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disorder caused by the expansion of CAG repeats in ATXN1 gene resulting in an expansion of polyglutamine repeats in the ATXN1 protein. Unfortunately, there has yet been any effective treatment so far for SCA1...

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Detalhes bibliográficos
Publicado no:Transl Neurodegener
Main Authors: Tsai, Pei-Jiun, Yeh, Chang-Ching, Huang, Wan-Jhen, Min, Ming-Yuan, Huang, Tzu-Hao, Ko, Tsui-Ling, Huang, Pei-Yu, Chen, Tien-Hua, Hsu, Sanford P. C., Soong, Bing-Wen, Fu, Yu-Show
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727337/
https://ncbi.nlm.nih.gov/pubmed/31508229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-019-0166-8
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