Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women

The placental transfer of maternal IgG is critical for infant protection against infectious pathogens. However, factors that modulate the placental transfer of IgG remain largely undefined. HIV-infected women have impaired placental IgG transfer, presenting a unique ‘‘disruption model’’ to define fa...

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Udgivet i:Cell
Main Authors: Martinez, David R., Fong, Youyi, Li, Shuk Hang, Yang, Fang, Jennewein, Madeleine F., Weiner, Joshua A., Harrell, Erin A., Mangold, Jesse F., Goswami, Ria, Seage, George R., Alter, Galit, Ackerman, Margaret E., Peng, Xinxia, Fouda, Genevieve G., Permar, Sallie R.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727200/
https://ncbi.nlm.nih.gov/pubmed/31204101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.05.046
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