טוען...
Disruption of the menin-MLL interaction triggers menin protein degradation via ubiquitin-proteasome pathway
Menin, a protein encoded by the MEN1 gene, suppresses cancers associated with multiple endocrine neoplasia type 1 (MEN1), but promotes the development of a subset of leukemia induced by mixed lineage leukemia (MLL)-derived fusion proteins (MLL-FPs). The crystal structure of menin indicates that it a...
שמור ב:
| הוצא לאור ב: | Am J Cancer Res |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
e-Century Publishing Corporation
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6726985/ https://ncbi.nlm.nih.gov/pubmed/31497350 |
| תגים: |
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