Patient-derived cancer organoid cultures to predict sensitivity to chemotherapy and radiation

OBJECTIVE: Cancer treatment is limited by inaccurate predictors of patient-specific therapeutic response. Therefore, some patients are exposed to unnecessary side effects and delays in starting effective therapy. A clinical tool that predicts treatment sensitivity for individual patients is needed....

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Pubblicato in:Clin Cancer Res
Autori principali: Pasch, Cheri A., Favreau, Peter F., Yueh, Alexander E., Babiarz, Christopher P., Gillette, Amani A., Sharick, Joe T., Karim, Mohammad Rezaul, Nickel, Kwangok P., DeZeeuw, Alyssa K., Sprackling, Carley M., Emmerich, Philip B., DeStefanis, Rebecca A., Pitera, Rosabella T., Payne, Susan N., Korkos, Demetra P., Clipson, Linda, Walsh, Christine M., Miller, Devon, Carchman, Evie H., Burkard, Mark E., Lemmon, Kayla K., Matkowskyj, Kristina A., Newton, Michael A., Ong, Irene M., Bassetti, Michael F., Kimple, Randall J., Skala, Melissa C., Deming, Dustin A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726566/
https://ncbi.nlm.nih.gov/pubmed/31175091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3590
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