A carregar...

AKT1(E17K) activates focal adhesion kinase and promotes melanoma brain metastasis

Alterations in the PI3K/AKT pathway occur in up to 70% of melanomas and are associated with disease progression. The three AKT paralogs are highly conserved but data suggest they have distinct functions. Activating mutations of AKT1 and AKT3 occur in human melanoma but their role in melanoma formati...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Kircher, David A., Trombetti, Kirby A., Silvis, Mark R., Parkman, Gennie L., Fischer, Grant M., Angel, Stephanie N., Stehn, Christopher M., Strain, Sean C., Grossmann, Allie H., Duffy, Keith L., Boucher, Kenneth M., McMahon, Martin, Davies, Michael A., Mendoza, Michelle C., VanBrocklin, Matthew W., Holmen, Sheri L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726552/
https://ncbi.nlm.nih.gov/pubmed/31138602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-1372
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!