Dissecting the stromal signaling and regulation of myeloid cells and memory effector T cells in pancreatic cancer

PURPOSE: Myeloid cells are a prominent immunosuppressive component within the stroma of pancreatic ductal adenocarcinoma(PDAC). Previously, targeting myeloid cells has had limited success. Here, we sought to target the myeloid cells through modifying a specific stromal component. EXPERIMENTAL DESIGN...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Blair, Alex B, Kim, Victoria M, Muth, Stephen T, Saung, May Tun, Lokker, Nathalie, Blouw, Barbara, Armstrong, Todd D, Jaffee, Elizabeth M, Tsujikawa, Takahiro, Coussens, Lisa M, He, Jin, Burkhart, Richard A, Wolfgang, Christopher L, Zheng, Lei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726532/
https://ncbi.nlm.nih.gov/pubmed/31186314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-4192
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