Dissecting the stromal signaling and regulation of myeloid cells and memory effector T cells in pancreatic cancer

PURPOSE: Myeloid cells are a prominent immunosuppressive component within the stroma of pancreatic ductal adenocarcinoma(PDAC). Previously, targeting myeloid cells has had limited success. Here, we sought to target the myeloid cells through modifying a specific stromal component. EXPERIMENTAL DESIGN...

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發表在:Clin Cancer Res
Main Authors: Blair, Alex B, Kim, Victoria M, Muth, Stephen T, Saung, May Tun, Lokker, Nathalie, Blouw, Barbara, Armstrong, Todd D, Jaffee, Elizabeth M, Tsujikawa, Takahiro, Coussens, Lisa M, He, Jin, Burkhart, Richard A, Wolfgang, Christopher L, Zheng, Lei
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726532/
https://ncbi.nlm.nih.gov/pubmed/31186314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-4192
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