Dissecting the stromal signaling and regulation of myeloid cells and memory effector T cells in pancreatic cancer

PURPOSE: Myeloid cells are a prominent immunosuppressive component within the stroma of pancreatic ductal adenocarcinoma(PDAC). Previously, targeting myeloid cells has had limited success. Here, we sought to target the myeloid cells through modifying a specific stromal component. EXPERIMENTAL DESIGN...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Blair, Alex B, Kim, Victoria M, Muth, Stephen T, Saung, May Tun, Lokker, Nathalie, Blouw, Barbara, Armstrong, Todd D, Jaffee, Elizabeth M, Tsujikawa, Takahiro, Coussens, Lisa M, He, Jin, Burkhart, Richard A, Wolfgang, Christopher L, Zheng, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726532/
https://ncbi.nlm.nih.gov/pubmed/31186314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-4192
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