Dissecting the stromal signaling and regulation of myeloid cells and memory effector T cells in pancreatic cancer

PURPOSE: Myeloid cells are a prominent immunosuppressive component within the stroma of pancreatic ductal adenocarcinoma(PDAC). Previously, targeting myeloid cells has had limited success. Here, we sought to target the myeloid cells through modifying a specific stromal component. EXPERIMENTAL DESIGN...

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Publicat a:Clin Cancer Res
Autors principals: Blair, Alex B, Kim, Victoria M, Muth, Stephen T, Saung, May Tun, Lokker, Nathalie, Blouw, Barbara, Armstrong, Todd D, Jaffee, Elizabeth M, Tsujikawa, Takahiro, Coussens, Lisa M, He, Jin, Burkhart, Richard A, Wolfgang, Christopher L, Zheng, Lei
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726532/
https://ncbi.nlm.nih.gov/pubmed/31186314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-4192
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