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Recycling endosomes in mature epithelia restrain tumorigenic signaling

The effects of polarized membrane trafficking in mature epithelial tissue on cell growth and cancer progression have not been fully explored in vivo. A majority of colorectal cancers have reduced and mislocalized Rab11, a small GTPase dedicated to trafficking of recycling endosomes. Patients with lo...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: D’Agostino, Luca, Nie, Yingchao, Goswami, Sayantani, Tong, Kevin, Yu, Shiyan, Bandyopadhyay, Sheila, Flores, Juan, Zhang, Xiao, Balasubramanian, Iyshwarya, Joseph, Ivor, Sakamori, Ryotaro, Farrell, Victoria, Li, Qi, Yang, Chung S., Gao, Bin, Ferraris, Ronaldo P., Yehia, Ghassan, Bonder, Edward M., Goldenring, James R., Verzi, Michael P., Zhang, Lanjing, Ip, Y. Tony, Gao, Nan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726494/
https://ncbi.nlm.nih.gov/pubmed/31239271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-4075
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