Hippo kinases LATS1/2 control human breast cell fate via crosstalk with ERα

Cell fate perturbations underlie many human diseases, including breast cancer(1,2). Unfortunately, the regulation of breast cell fate remains largely elusive. The mammary gland epithelium consists of differentiated luminal epithelial and basal myoepithelial cells, as well as undifferentiated stem ce...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Britschgi, Adrian, Duss, Stephan, Kim, Sungeun, Couto, Joana P., Brinkhaus, Heike, Koren, Shany, De Silva, Duvini, Mertz, Kirsten D., Kaup, Daniela, Varga, Zsuzsanna, Voshol, Hans, Vissieres, Alexandra, Leroy, Cedric, Roloff, Tim, Stadler, Michael B., Scheel, Christina H., Miraglia, Loren J., Orth, Anthony P., Bonamy, Ghislain M.C., Reddy, Venkateshwar A., Bentires-Alj, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726477/
https://ncbi.nlm.nih.gov/pubmed/28068668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20829
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