Hippo kinases LATS1/2 control human breast cell fate via crosstalk with ERα

Cell fate perturbations underlie many human diseases, including breast cancer(1,2). Unfortunately, the regulation of breast cell fate remains largely elusive. The mammary gland epithelium consists of differentiated luminal epithelial and basal myoepithelial cells, as well as undifferentiated stem ce...

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Published in:Nature
Main Authors: Britschgi, Adrian, Duss, Stephan, Kim, Sungeun, Couto, Joana P., Brinkhaus, Heike, Koren, Shany, De Silva, Duvini, Mertz, Kirsten D., Kaup, Daniela, Varga, Zsuzsanna, Voshol, Hans, Vissieres, Alexandra, Leroy, Cedric, Roloff, Tim, Stadler, Michael B., Scheel, Christina H., Miraglia, Loren J., Orth, Anthony P., Bonamy, Ghislain M.C., Reddy, Venkateshwar A., Bentires-Alj, Mohamed
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726477/
https://ncbi.nlm.nih.gov/pubmed/28068668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20829
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