Lobular carcinomas in situ display intra-lesion genetic heterogeneity and clonal evolution in the progression to invasive lobular carcinoma

PURPOSE: Lobular carcinoma in situ (LCIS) is a pre-invasive lesion of the breast. We sought to define its genomic landscape, whether intra-lesion genetic heterogeneity is present in LCIS, and the clonal relatedness between LCIS and invasive breast cancers. EXPERIMENTAL DESIGN: We reanalyzed whole-ex...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Clin Cancer Res
मुख्य लेखकों: Lee, Ju Youn, Schizas, Michail, Geyer, Felipe C., Selenica, Pier, Piscuoglio, Salvatore, Sakr, Rita A., Ng, Charlotte K. Y., Scarpa Carniello, Jose V., Towers, Russell, Giri, Dilip D., de Andrade, Victor P., Papanastasiou, Anastasios D., Viale, Agnes, Harris, Reuben S., Solit, David B., Weigelt, Britta, Reis-Filho, Jorge S., King, Tari A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726436/
https://ncbi.nlm.nih.gov/pubmed/30185420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1103
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