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Mechanistic insights into the phosphoryl transfer reaction in cyclin-dependent kinase 2: A QM/MM study

Cyclin-dependent kinase 2 (CDK2) is an important member of the CDK family exerting its most important function in the regulation of the cell cycle. It catalyzes the transfer of the gamma phosphate group from an ATP (adenosine triphosphate) molecule to a Serine/Threonine residue of a peptide substrat...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Recabarren, Rodrigo, Osorio, Edison H., Caballero, Julio, Tuñón, Iñaki, Alzate-Morales, Jans H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726203/
https://ncbi.nlm.nih.gov/pubmed/31483779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215793
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