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Exploration of the Activation Mechanism of the Epigenetic Regulator MLL3: A QM/MM Study
The mixed lineage leukemia 3 or MLL3 is the enzyme in charge of the writing of an epigenetic mark through the methylation of lysine 4 from the N-terminal domain of histone 3 and its deregulation has been related to several cancer lines. An interesting feature of this enzyme comes from its regulation...
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| Publicado no: | Biomolecules |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8301819/ https://ncbi.nlm.nih.gov/pubmed/34356675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11071051 |
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