Lanean...
Combination Treatment of Erythromycin and Furamidine Provides Additive and Synergistic Rescue of Mis-splicing in Myotonic Dystrophy Type 1 Models
[Image: see text] Myotonic dystrophy type 1 (DM1) is a multisystemic disease that presents with clinical symptoms including myotonia, cardiac dysfunction, and cognitive impairment. DM1 is caused by a CTG expansion in the 3′ UTR of the DMPK gene. The transcribed expanded CUG-repeat RNA sequester the...
Gorde:
| Argitaratua izan da: | ACS Pharmacol Transl Sci |
|---|---|
| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American
Chemical Society
2019
|
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6726129/ https://ncbi.nlm.nih.gov/pubmed/31485578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00020 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|