Tau Protein Is Cross-Linked by Transglutaminase in P301L Tau Transgenic Mice

The microtubule-associated protein tau is highly soluble under physiological conditions. However, in tauopathies, tau protein aggregates into insoluble filaments and neurofibrillary tangles (NFTs). The mechanisms underlying the formation of tau filaments and NFTs in tauopathies remain unclear. Sever...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Halverson, Robyn A., Lewis, Jada, Frausto, Shanti, Hutton, Mike, Muma, Nancy A.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2005
Subjects:
Neurobiology of Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725970/
https://ncbi.nlm.nih.gov/pubmed/15689560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3263-04.2005
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