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Filamentous Tau in Oligodendrocytes and Astrocytes of Transgenic Mice Expressing the Human Tau Isoform with the P301L Mutation

We recently reported a transgenic mouse line (JNPL3) that expresses mutant (P301L) tau and develops neurofibrillary tangles composed of filamentous tau aggregates. Here we show that these mice have abnormal tau filaments not only in neurons, but also in oligodendrocytes and astrocytes. Similar resul...

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Bibliografski detalji
Glavni autori: Lin, Wen-Lang, Lewis, Jada, Yen, Shu-Hui, Hutton, Michael, Dickson, Dennis W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851123/
https://ncbi.nlm.nih.gov/pubmed/12507904
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