Triple Knock-Out of CNTF, LIF, and CT-1 Defines Cooperative and Distinct Roles of these Neurotrophic Factors for Motoneuron Maintenance and Function

Members of the ciliary neurotrophic factor (CNTF)-leukemia inhibitory factor (LIF) gene family play an essential role for survival of developing and postnatal motoneurons. When subunits of the shared receptor complex are inactivated by homologous recombination, the mice die at approximately birth an...

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Pubblicato in:J Neurosci
Autori principali: Holtmann, Bettina, Wiese, Stefan, Samsam, Mohtashem, Grohmann, Katja, Pennica, Diane, Martini, Rudolf, Sendtner, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2005
Soggetti:
Neurobiology of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725944/
https://ncbi.nlm.nih.gov/pubmed/15716414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4249-04.2005
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