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Ciliary neurotrophic factor (CNTF) protects retinal cone and rod photoreceptors by suppressing excessive formation of the visual pigments

The retinal pigment epithelium (RPE)-dependent visual cycle provides 11-cis-retinal to opsins in the photoreceptor outer segments to generate functional visual pigments that initiate phototransduction in response to light stimuli. Both RPE65 isomerase of the visual cycle and the rhodopsin visual pig...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Li, Songhua, Sato, Kota, Gordon, William C., Sendtner, Michael, Bazan, Nicolas G., Jin, Minghao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166737/
https://ncbi.nlm.nih.gov/pubmed/30115683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004008
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