Triple Knock-Out of CNTF, LIF, and CT-1 Defines Cooperative and Distinct Roles of these Neurotrophic Factors for Motoneuron Maintenance and Function

Members of the ciliary neurotrophic factor (CNTF)-leukemia inhibitory factor (LIF) gene family play an essential role for survival of developing and postnatal motoneurons. When subunits of the shared receptor complex are inactivated by homologous recombination, the mice die at approximately birth an...

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Vydáno v:J Neurosci
Hlavní autoři: Holtmann, Bettina, Wiese, Stefan, Samsam, Mohtashem, Grohmann, Katja, Pennica, Diane, Martini, Rudolf, Sendtner, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2005
Témata:
Neurobiology of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725944/
https://ncbi.nlm.nih.gov/pubmed/15716414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4249-04.2005
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