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Effect of Domain Interaction on Apolipoprotein E Levels in Mouse Brain

Apolipoprotein (apo) E4 is a risk factor for heart disease, Alzheimer's disease, and other forms of neurodegeneration, but the underlying mechanisms are unknown. Domain interaction, a structural property that distinguishes apoE4 from apoE2 and apoE3, results in more rapid turnover and lower pla...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ramaswamy, Gayathri, Xu, Qin, Huang, Yadong, Weisgraber, Karl H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725862/
https://ncbi.nlm.nih.gov/pubmed/16291938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1922-05.2005
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