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Introduction of human apolipoprotein E4 “domain interaction” into mouse apolipoprotein E
Human apolipoprotein E4 (apoE4) binds preferentially to lower density lipoproteins, including very low density lipoproteins, and is associated with increased risk of atherosclerosis and neurodegenerative disorders, including Alzheimer's disease. This binding preference is the result of the pres...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC58773/ https://ncbi.nlm.nih.gov/pubmed/11553788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.201279298 |
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