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Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS
Apolipoprotein (apo) E has roles beyond lipoprotein metabolism. The detrimental effects of apoE4 in cardiovascular, neurological, and infectious diseases correlate with its structural features (e.g., domain interaction) that distinguish it from apoE3 and apoE2. Structure/function studies revealed th...
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| Main Authors: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Biochemistry and Molecular Biology
2009
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674716/ https://ncbi.nlm.nih.gov/pubmed/19106071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R800069-JLR200 |
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