Binding of the Positron Emission Tomography Tracer Pittsburgh Compound-B Reflects the Amount of Amyloid-β in Alzheimer's Disease Brain But Not in Transgenic Mouse Brain

During the development of in vivo amyloid imaging agents, an effort was made to use micro-positron emission tomography (PET) imaging in the presenilin-1 (PS1)/amyloid precursor protein (APP) transgenic mouse model of CNS amyloid deposition to screen new compounds and further study Pittsburgh Compoun...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Neurosci
Autori principali: Klunk, William E., Lopresti, Brian J., Ikonomovic, Milos D., Lefterov, Iliya M., Koldamova, Radosveta P., Abrahamson, Eric E., Debnath, Manik L., Holt, Daniel P., Huang, Guo-feng, Shao, Li, DeKosky, Steven T., Price, Julie C., Mathis, Chester A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2005
Soggetti:
Cellular/Molecular
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725842/
https://ncbi.nlm.nih.gov/pubmed/16291932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2990-05.2005
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi