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Carbon 11–Labeled Pittsburgh Compound B and Carbon 11–Labeled (R)-PK11195 Positron Emission Tomographic Imaging in Alzheimer Disease

BACKGROUND: Alzheimer disease (AD) is defined neuropathologically by the presence of neurofibrillary tangles and plaques associated with tau and β-amyloid protein deposition. The colocalization of microglia and β-amyloid plaques has been widely reported in pathological examination of AD and suggests...

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Bibliografiske detaljer
Main Authors: Wiley, Clayton A., Lopresti, Brian J., Venneti, Sriram, Price, Julie, Klunk, William E., DeKosky, Steven T., Mathis, Chester A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666881/
https://ncbi.nlm.nih.gov/pubmed/19139300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2008.511
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