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Akt Contributes to Neuroprotection by Hypothermia against Cerebral Ischemia in Rats
Activation of the Akt/protein kinase B (PKB) kinase pathway can be neuroprotective after stroke. Akt is activated by growth factors via a phosphorylation-dependent pathway involving the kinases phosphoinositide 3 (PI3) kinase and phosphoinositide-dependent protein kinase-1 (PDK1) and is negatively r...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6725740/ https://ncbi.nlm.nih.gov/pubmed/16237183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3163-05.2005 |
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