Akt Contributes to Neuroprotection by Hypothermia against Cerebral Ischemia in Rats

Activation of the Akt/protein kinase B (PKB) kinase pathway can be neuroprotective after stroke. Akt is activated by growth factors via a phosphorylation-dependent pathway involving the kinases phosphoinositide 3 (PI3) kinase and phosphoinositide-dependent protein kinase-1 (PDK1) and is negatively r...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Zhao, Heng, Shimohata, Takayoshi, Wang, Jade Q., Sun, Guohua, Schaal, David W., Sapolsky, Robert M., Steinberg, Gary K.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2005
Fag:
Neurobiology of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725740/
https://ncbi.nlm.nih.gov/pubmed/16237183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3163-05.2005
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