Vulnerability of Dentate Granule Cells to Disruption of Arc Expression in Human Amyloid Precursor Protein Transgenic Mice

Activity-induced expression of Arc is necessary for maintenance of long-term potentiation and for memory consolidation. In transgenic (TG) mice with neuronal production of human amyloid precursor protein (hAPP) and hAPP-derived amyloid-β (Aβ) peptides, basal Arc expression was reduced primarily in g...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Palop, Jorge J., Chin, Jeannie, Bien-Ly, Nga, Massaro, Catherine, Yeung, Bertrand Z., Yu, Gui-Qiu, Mucke, Lennart
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725729/
https://ncbi.nlm.nih.gov/pubmed/16237173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2829-05.2005
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