Neurocognitive and Psychotiform Behavioral Alterations and Enhanced Hippocampal Long-Term Potentiation in Transgenic Mice Displaying Neuropathological Features of Human α-Mannosidosis

Mice with α-mannosidase gene inactivation provide an experimental model for α-mannosidosis, a lysosomal storage disease with severe neuropsychological and psychopathological complications. Neurohistological alterations in these mice were similar to those in patients and included vacuolations and axo...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: D'Hooge, Rudi, Lüllmann-Rauch, Renate, Beckers, Tom, Balschun, Detlef, Schwake, Michael, Reiss, Karina, von Figura, Kurt, Saftig, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725435/
https://ncbi.nlm.nih.gov/pubmed/16014715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0283-05.2005
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