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Inhibition by Spinal μ- and δ-Opioid Agonists of Afferent-Evoked Substance P Release

Opioid μ- and δ-receptors are present on the central terminals of primary afferents, where they are thought to inhibit neurotransmitter release. This mechanism may mediate analgesia produced by spinal opiates; however, when they used neurokinin 1 receptor (NK1R) internalization as an indicator of su...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Kondo, Ichiro, Marvizon, Juan Carlos G., Song, Bingbing, Salgado, Frances, Codeluppi, Simone, Hua, Xiao-Ying, Yaksh, Tony L.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725388/
https://ncbi.nlm.nih.gov/pubmed/15814796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0252-05.2005
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