A Highly Specific Inhibitor of Matrix Metalloproteinase-9 Rescues Laminin from Proteolysis and Neurons from Apoptosis in Transient Focal Cerebral Ischemia

Neuronal cell death occurs during many neurodegenerative disorders and stroke. The aberrant, excessive activity of matrix metalloproteinases (MMPs), especially MMP-9, contributes directly to neuron apoptosis and brain damage (Rosenberg et al., 1996; Asahi et al., 2001; Gu et al., 2002; Horstmann et...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Gu, Zezong, Cui, Jiankun, Brown, Stephen, Fridman, Rafael, Mobashery, Shahriar, Strongin, Alex Y., Lipton, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725288/
https://ncbi.nlm.nih.gov/pubmed/16000631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1563-05.2005
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