A Role for p38 Mitogen-Activated Protein Kinase in the Regulation of the Serotonin Transporter: Evidence for Distinct Cellular Mechanisms Involved in Transporter Surface Expression

The serotonin transporter (SERT) is regulated by various signaling mechanisms that may operate to maintain appropriate levels of synaptic serotonin (5-HT). We demonstrate that one of the mitogen-activated protein kinases (MAPKs), p38 MAPK, regulates SERT. Treatment of rat midbrain synaptosomes with...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Samuvel, Devadoss J., Jayanthi, Lankupalle D., Bhat, Narayan R., Ramamoorthy, Sammanda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2005
Schlagworte:
Cellular/Molecular
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725216/
https://ncbi.nlm.nih.gov/pubmed/15634764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3754-04.2005
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