Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase

Human serotonin [5-hydroxytryptamine (5-HT)] transporters (hSERT, 5HTT, and SLC6A4) inactivate 5-HT after release and are prominent targets for therapeutic intervention in mood, anxiety, and obsessive-compulsive disorders. Multiple hSERT coding variants have been identified, although to date no comp...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Prasad, Harish C., Zhu, Chong-Bin, McCauley, Jacob L., Samuvel, Devadoss J., Ramamoorthy, Sammanda, Shelton, Richard C., Hewlett, William A., Sutcliffe, James S., Blakely, Randy D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2005
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183547/
https://ncbi.nlm.nih.gov/pubmed/16055563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501432102
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