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β-Amyloid-Stimulated Microglia Induce Neuron Death via Synergistic Stimulation of Tumor Necrosis Factor α and NMDA Receptors
Although abundant reactive microglia are found associated with β-amyloid (Aβ) plaques in Alzheimer's disease (AD) brains, their contribution to cell loss remains speculative. A variety of studies have documented the ability of Aβ fibrils to directly stimulate microglia in vitro to assume a neur...
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| Veröffentlicht in: | J Neurosci |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6725188/ https://ncbi.nlm.nih.gov/pubmed/15758166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4998-04.2005 |
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